New fluorinated and nonfluorinated sugar alkenylphosphonates were obtained. In all cases 1,2;5,6-di-O-isopropylidene-α-d-glucofuranose was used as the starting material. The synthesis of alkenylphosphonates was based on Horner-Wadsworth-Emmons olefination. The process led to products with E-stereochemistry exclusively or predominately. Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
Monika Bilska-Markowska, Marcin Kaźmierczak. Synthesis of fluorinated and nonfluorinated sugar alkenylphosphonates via highly stereoselective Horner-Wadsworth-Emmons olefination. Carbohydrate research. 2023 Nov;533:108941
PMID: 37717483
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