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Ring translocation switches and shuttles featuring a macrocycle (or a ring molecule) navigating between two or more stations continue to attract attention. While the vast majority of these systems are developed in organic solvents, the cucurbituril (CB) macrocycles are ideally suited to prepare such systems in water. Indeed, their stability and their relatively high affinity for relevant guest molecules are key attributes toward translating the progresses made in organic solvents, into water. In this concept article, we summarize the findings, key advances and multiple possibilities offered by CBs toward advanced molecular switches and shuttles in water. © 2023 Wiley-VCH GmbH.

Citation

Anthony Kermagoret, David Bardelang. The Diversity of Cucurbituril Molecular Switches and Shuttles. Chemistry (Weinheim an der Bergstrasse, Germany). 2023 Sep 19:e202302114


PMID: 37725407

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