Association between SARS-CoV-2 infections during pregnancy and preterm live birth.

Influenza and other respiratory viruses 2023 Sep

filter terms:

We examined associations between mild or asymptomatic prenatal SARS-CoV-2 infection and preterm live birth in a prospective cohort study. During August 2020-October 2021, pregnant persons were followed with systematic surveillance for RT-PCR or serologically confirmed SARS-CoV-2 infection until pregnancy end. The association between prenatal SARS-CoV-2 infection and preterm birth was assessed using Cox proportional-hazards regression. Among 954 pregnant persons with a live birth, 185 (19%) had prenatal SARS-CoV-2 infection and 123 (13%) had preterm birth. The adjusted hazard ratio for the association between SARS-CoV-2 infection and preterm birth was 1.28 (95% confidence interval 0.82-1.99, p = 0.28), although results did not reach statistical significance. © 2023 Abt Associates and The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.

Citation

Sarita Mohanty, Alan T Tita, Michael Varner, Melissa S Stockwell, Gabriella Newes-Adeyi, Ashley N Battarbee, Lawrence Reichle, Tyler Morrill, Michael Daugherty, Mirella Mourad, Raul A Silverio Francisco, Kate Woodworth, Kristina Wielgosz, Romeo Galang, Pete Maniatis, Vera Semenova, Fatimah S Dawood. Association between SARS-CoV-2 infections during pregnancy and preterm live birth. Influenza and other respiratory viruses. 2023 Sep;17(9):e13192