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The pharmacokinetics of theophylline as a sirup (5 or 6 mg . kg-1 bodyweight) were studied in 6 volunteers before and after association with idrocilamide. The results showed an increase in theophylline half-life, a decrease in clearance and a slight decrease in volume of distribution.

Citation

C Lacroix, J Nouveau, P Hubscher, D Tardif, M Ray, J P Goulle. Influence of idrocilamide on the metabolism of theophylline]. Revue de pneumologie clinique. 1986;42(3):164-6

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PMID: 3775181

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