Pituitary gland agouti-related peptide cells: Novel player controlling glucose metabolism.

Kei Takahashi, Hideki Katagiri

Journal of diabetes investigation 2024 Jan

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The liver synthesizes and releases bile acids into the gut. Bile acids, either directly or indirectly, inhibit agouti-related peptide (AGRP)-B cells in the pars tuberalis of the pituitary gland. AGRP-B cells are assumed to promote pancreatic insulin secretion and/or to improve insulin sensitivities in insulin sensitive organs, resulting in improved glucose tolerance. © 2023 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.

Citation

Kei Takahashi, Hideki Katagiri. Pituitary gland agouti-related peptide cells: Novel player controlling glucose metabolism. Journal of diabetes investigation. 2024 Jan;15(1):67-69