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A new chink in cancer's armor: Unleashing cell death by selective PP5 inhibition.
Cell chemical biology 2023 Oct 19Sizes of these terms reflect their relevance to your search.
Serine/threonine protein phosphatases play a significant role in the survival and propagation of multiple cancers. In this issue of Cell Chemical Biology, Ahanin et al.1 demonstrate that protein phosphatase 5 (PP5) dephosphorylates and inactivates the cell death effector protein FADD independently of Hsp90, and they identify a selective PP5 inhibitor as a new therapeutic strategy for renal cancer. Copyright © 2023 Elsevier Ltd. All rights reserved.
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Patricija van Oosten-Hawle. A new chink in cancer's armor: Unleashing cell death by selective PP5 inhibition. Cell chemical biology. 2023 Oct 19;30(10):1186-1188
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PMID: 37863031
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