Bacteria manipulate host cells with channel-forming effectors.

Yukun Liu, Shuguo Hou

Trends in microbiology 2024 Jan

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Bacterial pathogens deliver effectors into host cells mostly to manipulate signaling and metabolic molecules, thereby subverting host immunity. A recent study by Nomura et al. demonstrates that certain effectors create membrane channels in host cells, enabling bacteria to access water and solutes for multiplication. Copyright © 2023 Elsevier Ltd. All rights reserved.