The Best Psoriasis Medications Emerge.

Andrew Blauvelt, Megan H Noe

JAMA dermatology 2024 Jan 01

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What are the most effective systemic medications to treat plaque psoriasis? The most effective drugs for psoriasis were infliximab, bimekizumab, ixekizumab, and risankizumab, and the clinical effectiveness was similar when these 4 drugs were compared against one another. No statistically significant differences in serious adverse events were identified in any of the drugs compared with placebo. The main limitations of this meta-analysis include the lack of assessment of clinical effectiveness beyond 52 weeks and the lack of safety assessments for nonserious adverse events.