Targeting immunogenic cell death for glioma immunotherapy.

Immunogenic cell death (ICD) arouses great interest in targeting glioma, the most common primary brain tumor, to achieve boosted immunotherapy. We discuss the unexpected findings on the induction of Th17 immunity by ICD and propose the best design for dendritic cell (DC)-based vaccines loaded with whole glioma lysates obtained after ICD inducers. Copyright © 2023 Elsevier Inc. All rights reserved.

Citation

Tatiana A Mishchenko, Victoria D Turubanova, Ekaterina N Gorshkova, Olga Krysko, Maria V Vedunova, Dmitri V Krysko. Targeting immunogenic cell death for glioma immunotherapy. Trends in cancer. 2024 Jan;10(1):8-11

Mesh Tags

Substances

PMID: 37973489

search → result