Therapeutic apheresis in renal transplantation: An update.

Therapeutic apheresis (TA) plays a significant role in various aspects of renal transplantation. It has been a necessary preconditioning component in ABO incompatible kidney transplants and an important modality in the removal of anti-human leukocyte antigen (HLA) antibodies both in the context of desensitization protocols that have been developed to allow highly sensitized kidney transplant candidates to be successfully transplanted and as treatment of antibody mediated rejection episodes post transplantation. In addition, TA has been used with various results for the management of recurrent focal segmental glomerulosclerosis. The purpose of this review is to examine the evidence supporting the application of TA as an adjunctive therapeutic option to immunosuppressive agents in protocols both before and after kidney transplantation. Copyright © 2023 Elsevier Ltd. All rights reserved.

Citation

Christina Melexopoulou, Vassilis Filiopoulos, Smaragdi Marinaki. Therapeutic apheresis in renal transplantation: An update. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 2024 Feb;63(1):103844

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PMID: 37978039

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