IL-6 Enhances the Viability and Invasion Ability of Prostate Cancer Cells.

Kai Cheng, Christopher Batbatan, Qingmei Jia

Studies in health technology and informatics 2023 Nov 23

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Prostate cancer is a slow-growing cancer whose incidence increases with age. IL-6 expression is significantly increased in a variety of malignant tumor stroma, which is a key factor involved in the association between inflammation and tumor. So as to investigate how prostate cancer works, recombinant IL-6 was used to stimulate human prostate cancer cells (PC-3). After treatment for 24,48,72h, the viability of cancer cells was detected by CCK-8 experiment. The effect of recombinant IL-6 on the invasion of prostate cancer cells was analyzed by Transwell experiment. The results showed that IL-6 can increase the viability of prostate cancer cells and facilitate the invasion of prostate cancer cells.

Citation

Kai Cheng, Christopher Batbatan, Qingmei Jia. IL-6 Enhances the Viability and Invasion Ability of Prostate Cancer Cells. Studies in health technology and informatics. 2023 Nov 23;308:521-526