Applications of guar gum polysaccharide for pharmaceutical drug delivery: A review.

Bio-based materials are rapidly replacing synthetic materials owing to their significant biomedical applications, easy availability, nontoxicity, biodegradability and biocompatibility. Guar gum (GG) is a plant-derived biocompatible and biodegradable polymeric compound found abundantly in nature. It is a non-ionic, hydrophilic carbohydrate and is a cost-effective hydrocolloid polysaccharide considered as a wonderful representative of the new generation of plant gums. Various composites of guar gum with other polymers have been reported in last few decades and they are extensively used in different industries like food, textile, mining, petrochemical, paper and explosives etc. Easy availability, non-toxicity, eco-friendly and biodegradable nature of GG has made it ideal candidate for for drug delivery (DD) applications. GG based hydrogels, films, scaffolds and nanoparticles have been explored widely for their DD applications. These non-toxic DD carriers can be used for targeted drug delivery. This review article directs the current efforts and improvements on GG and GG-based materials to be used in DD. Copyright © 2023 Elsevier B.V. All rights reserved.

Citation

Nyla Amjed, Muhammad Zeshan, Ariba Farooq, Sadaf Naz. Applications of guar gum polysaccharide for pharmaceutical drug delivery: A review. International journal of biological macromolecules. 2024 Feb;257(Pt 1):128390

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PMID: 38043657

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