Safety of fluoroquinolones.

J Barberán, A de la Cuerda, M I Tejeda González, A López Aparicio, C Monfort Vinuesa, A Ramos Sánchez, L C Barberán

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 2024 Apr

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Fluoroquinolones (FQs) are one of the most commonly prescribed classes of antibiotics. Although they were initially well tolerated in randomized clinical trials, subsequent epidemiological studies have reported an increased risk of threatening, severe, long-lasting, disabling and irreversible adverse effects (AEs), related to neurotoxicity and collagen degradation, such as tendonitis, Achilles tendon rupture, aortic aneurysm, and retinal detachment. This article reviews the main potentially threatening AEs, the alarms issued by regulatory agencies and therapeutic alternatives. ©The Author 2023. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).

Citation

J Barberán, A de la Cuerda, M I Tejeda González, A López Aparicio, C Monfort Vinuesa, A Ramos Sánchez, L C Barberán. Safety of fluoroquinolones. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia. 2024 Apr;37(2):127-133