Development of a tool to calculate the probability of hypocalcemia after total thyroidectomy: a prospective study.

This study aimed to evaluate the ability of the percentage of decrease in serum PTH level in the first 8 h after total thyroidectomy (TT) to predict hypocalcemia requiring Ca supplementation and develop a tool to predict it. 97 patients who underwent TT with measurement of preoperative parathyroid hormone (PTH) levels were prospectively evaluated 1 and 8 h after TT; postoperative magnesium (Mg2PO) and phosphorus levels were evaluated on the 2nd day after surgery. The percentage of decrease in PTH level 1 h (%dPTH1h) and 8 h (%dPTH8h) postoperatively and predictors of hypocalcemia requiring Ca supplementation were evaluated and an equation was developed to predict this outcome. %dPTH1h (p = 0.002), %dPTH8h (p = 0.001) and (Mg2PO) (p < 0.01) were isolated predictors of postoperative hypocalcemia requiring Ca supplementation. The data obtained led to the development of two tools to predict this complication. The percentage of decrease in PTH level 1 h and 8 h postoperatively and the magnesium level on the 2nd day after surgery were predictors of more severe hypocalcemia, and an auxiliary tool for predicting this complication was developed. © 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Citation

Carlos Segundo Paiva Soares, Katia Hiromoto Koga, Sonia Marta Moriguchi, Simone Antunes Terra, José Vicente Tagliarini, Pedro Henrique Dalmolin de Vasconcelos Affonso, Monise da Silva Pechutti, Gláucia Maria Ferreira da Silva Mazeto. Development of a tool to calculate the probability of hypocalcemia after total thyroidectomy: a prospective study. Langenbeck's archives of surgery. 2024 Jan 09;409(1):33

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PMID: 38195723

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