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Integrating a hydrogel electroosmotic pump with a parylene C-coated porous microneedle (PMN) is developed for transdermal drug delivery applications. The hydrogel pump is fabricated by combining an anionic and a cationic hydrogel to generate enhanced electroosmosis flow (EOF) to drive the transportation of molecules via PMN.


Gaobo Wang, Kosuke Kato, Izuru Aoki, Sae Ichinose, Daisuke Inoue, Soichiro Tottori, Matsuhiko Nishizawa. Transdermal drug delivery using a porous microneedle device driven by a hydrogel electroosmotic pump. Journal of materials chemistry. B. 2024 Feb 07;12(6):1490-1494

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PMID: 38234189

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