Predictive and prognostic biomarkers in gastrointestinal tract tumours.

Klaudia M Nowak, Runjan Chetty

Pathology 2024 Mar

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Tumours of the gastrointestinal tract represent nearly a quarter of all newly diagnosed tumours diagnosed in 2019. Various treatment modalities for gastrointestinal cancers exist, some of which may be guided by biomarkers. Biomarkers act as gauges of either normal or pathogenic processes or responses to an exposure or intervention. They come in many forms. This review explores established and potential molecular/immunohistochemical (IHC) predictive and prognostic biomarkers of the gastrointestinal tract. Copyright © 2024 Royal College of Pathologists of Australasia. Published by Elsevier B.V. All rights reserved.