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In a recent issue of Cell, Dezfulian et al. develop a genome-scale platform to enable high-throughput identification of CD4+ T cell epitopes. This platform enables unbiased screens to discover antigens recognized by CD4+ T cells in cancer, infectious diseases, and autoimmunity. Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.


Blake E Smith, Amanda O Chan, Michael E Birnbaum. Re-centauring T cell antigen discovery around CD4+ T cells. Cell reports methods. 2024 Jan 22;4(1):100694

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PMID: 38262348

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