There are many challenges to obtain antigen-negative, crossmatch compatible blood for a patient with multiple alloantibodies. We present a case report of a 31-year-old female patient with a recurrent pontine cavernoma who was to undergo a neurosurgical procedure. We identified alloantibodies anti-Fya and anti-c in her blood sample. To meet her intraoperative blood requirement, we attempted with autologous blood transfusion using both predeposit autologous donation and acute normovolemic hemodilution. Autologous blood alone was sufficient despite anticipating surgical blood loss and a postoperative surgical site infection. Copyright: © 2022 Asian Journal of Transfusion Science.
Angel Mary Sam, Amita Radhakrishnan Nair, Debasish Gupta. Autologous blood transfusion in a neurosurgical patient with multiple alloantibodies. Asian journal of transfusion science. 2023 Jul-Dec;17(2):276-278
PMID: 38274966
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