Clear Search sequence regions


  • lipids (1)
  • mass (6)
  • peptides (3)
  • studies samples (1)
  • Sizes of these terms reflect their relevance to your search.

    Mass spectrometry imaging (MSI) has become increasingly utilized in the analysis of biological molecules. MSI grants the ability to spatially map thousands of molecules within one experimental run in a label-free manner. While MSI is considered by most to be a qualitative method, recent advancements in instrumentation, sample preparation, and development of standards has made quantitative MSI (qMSI) more common. In this feature article, we present a tailored review of recent advancements in qMSI of therapeutics and biomolecules such as lipids and peptides/proteins. We also provide detailed experimental considerations for conducting qMSI studies on biological samples, aiming to advance the methodology.

    Citation

    Joseph H Holbrook, Gabrielle E Kemper, Amanda B Hummon. Quantitative mass spectrometry imaging: therapeutics & biomolecules. Chemical communications (Cambridge, England). 2024 Feb 20;60(16):2137-2151

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 38284765

    View Full Text