In this issue of JEM, Peng et al. (https://doi.org/10.1084/jem.20230124) identify inositol polyphosphate 4-phosphatase type II (encoded by Inpp4b) as an important enzyme for tissue-resident ILC1 and NK cell survival, signal transduction, and anti-tumor immunity. © 2024 Chen and Mortha.
Zi Yan Chen, Arthur Mortha. INPP4B ensures that ILC1s and NK cells set up a productive home office. The Journal of experimental medicine. 2024 Mar 04;221(3)
PMID: 38329467
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