Mushrooms are distinguished as important food-containing polysaccharides possessing potent anti-inflammatory and immunomodulating properties. These compounds belong mostly to polysaccharides that are mostly β-D-glucans. Among them, β-1,3-glucan with β-1,6 side chains of glucose residues, has more important roles in their properties. In this review, we have introduced polysaccharides mainly from Lentinula edodes and Pleurotus citrinopileatus with anti-inflammatory and immunomodulating properties. In addition, the mechanisms of activation of their physiological properties and signal cascade are also reviewed. Copyright © 2024 Elsevier Ltd. All rights reserved.
Masashi Mizuno, Ken-Ichiro Minato. Anti-inflammatory and immunomodulatory properties of polysaccharides in mushrooms. Current opinion in biotechnology. 2024 Apr;86:103076
PMID: 38364705
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