Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

In this case series, a perioperative anticoagulation protocol for microvascular head and neck surgery in patients with thrombophilia is presented. Microvascular free-flap surgery is a standard procedure in head and neck surgery with high success rates. Nevertheless, flap loss-which is most often caused by thrombosis-can occur and has far-reaching consequences, such as functional impairment, prolonged hospitalization, and increased costs. The risk of flap loss owing to thrombosis is significantly increased in patients with thrombophilia. Therefore, perioperative anticoagulation is mandatory. To date, no perioperative anticoagulation protocol exists for these high-risk patients. We present three exemplary male Caucasian patients aged 53-57 years with free flap loss owing to an underlying, hidden thrombophilia. We present a modified anticoagulation protocol for microvascular surgery in these high-risk patients, enabling successful microsurgical reconstruction. © 2024. The Author(s).

Citation

Julian Faber, Frank Schuster, Stefan Hartmann, Roman C Brands, Andreas Fuchs, Anton Straub, Markus Fischer, Urs Müller-Richter, Christian Linz. Successful microvascular surgery in patients with thrombophilia in head and neck surgery: a case series. Journal of medical case reports. 2024 Feb 28;18(1):119

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 38414080

View Full Text