Tailored and universal parallel transmit broadband pulses for homogeneous 3D excitation of the human heart at 7T.

To research and evaluate the performance of broadband tailored kT-point pulses (TP) and universal pulses (UP) for homogeneous excitation of the human heart at 7T. Relative 3D B 1 + $$ {\mathrm{B}}_1^{+} $$ -maps of the thorax were acquired from 29 healthy volunteers. TP and UP were designed using the small-tip-angle approximation for a different composition of up to seven resonance frequencies. TP were computed for each of the 29 B 1 + $$ {\mathrm{B}}_1^{+} $$ -maps, and UPs were calculated using 22 B 1 + $$ {\mathrm{B}}_1^{+} $$ -maps and tested in seven testcases. The performance of the pulses was analyzed using the coefficient of variation (CV) in the 3D heart volumes. The 3D gradient-echo (GRE) scans were acquired for the seven testcases to qualitatively validate the B 1 + $$ {\mathrm{B}}_1^{+} $$ -predictions. Single- and double-frequency optimized pulses achieved homogeneity in flip angle (FA) for the frequencies they were optimized for, while the broadband pulses achieved uniformity in FA across a 1300 Hz frequency range. Broadband TP and UP can be used for homogeneous excitation of the heart volume across a 1300 Hz frequency range, including the water and the main six fat peaks, or with longer pulse durations and higher FAs for a smaller transmit bandwidth. Moreover, despite large inter-volunteer variations, broadband UP can be used for calibration-free 3D heart FA homogenization in time-critical situations. © 2024 Physikalisch‐Technische Bundesanstalt. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.

Citation

Christoph Stefan Aigner, Sebastian Dietrich-Conzelmann, Max Lutz, Felix Krüger, Sebastian Schmitter. Tailored and universal parallel transmit broadband pulses for homogeneous 3D excitation of the human heart at 7T. Magnetic resonance in medicine. 2024 Aug;92(2):730-740

Mesh Tags

PMID: 38440957

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