Botanical Briefs: Neem Oil (Azadirachta indica).

Nina Patel, Michael Knabel, Jodi Speiser

Cutis 2024 Jan

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Azadirachta indica, commonly known as neem, has many uses as a natural remedy. We review and discuss the pharmacologic, biologic, and medicinal properties of neem in disease management. We also report a rare clinical case of a 77-year-old man who presented with a hypopigmented rash on the lower back, bilateral flanks, and buttocks after 6 months of repeated application of neem oil to treat persistent arthritis and lower back pain.