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IL-4-ever young: Type 2 cytokine signaling in macrophages slows aging.
Immunity 2024 Mar 12Sizes of these terms reflect their relevance to your search.
Macrophages activated via the IL-4 receptor possess non-immune functions that support tissue homeostasis, but their specific role in aging is unknown. In this issue of Immunity, Zhou et al. show that IL-4 extends lifespan by inducing DNA repair pathways that protect macrophages from cellular senescence. Copyright © 2024 Elsevier Inc. All rights reserved.
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Conor M Finlay, Judith E Allen. IL-4-ever young: Type 2 cytokine signaling in macrophages slows aging. Immunity. 2024 Mar 12;57(3):403-406
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PMID: 38479355
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