Dapoxetine versus glans penis injection with hyaluronic acid gel in treatment of premature ejaculation.

to compare the results of using Dapoxetine and HA (hyaluronic acid) gel injection by Five puncture technique in the treatment of premature ejaculation (PE). 100 sexually active heterosexuals circumcised males with lifelong PE were included in the study. Group A patients were treated with on-demand Dapoxetine, while group B was treated with HA gel glans penis injection using a five-puncture technique. Both groups were evaluated at 1st,3rd and 6th months post-treatment using IELT. There were no significant differences between both groups regarding patient demographic. Mean pretreatment IELT in groups A and B were 45.82 ± 7.44 and 46.18 ± 7.82 receptively. There was no significant difference between both groups. After treatment, both groups show significant ILET improvement during the 1st,3rd, and 6th months follow-up with a P value < 0.001. However, when comparing the improvement of ILET in group A (Dapoxetine) and group B (HA injection), there were high significance differences in favor of group B in the 1st,3rd, and 6th-month follow-up. Although both treatment modalities have improved IELT and premature ejaculation, but HA injection with five punctures technique was significantly better than oral Dapoxetine with self-limited side effects. © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Citation

Ibrahim M Ibrahim, Moustafa Mohamed, Mostafa Kamel, Lotfy Elbendary, Almaqtouf Mohamed, Mohamed S Elderey. Dapoxetine versus glans penis injection with hyaluronic acid gel in treatment of premature ejaculation. Arab journal of urology. 2024;22(2):75-80

PMID: 38481413

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