Haemophilus influenzae endocarditis: a case report and literature review.

Nadim Jaafar, Akshay Duddu, Siddartha Guru, Ibukunolupo Oni

Infection 2024 Aug

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Haemophilus influenzae (HI) is an exceedingly rare cause of infective endocarditis (IE). We present a case of a 90-year-old female diagnosed with HI-IE involving the native tricuspid valve in the absence of traditional risk factors for right-sided endocarditis. She was treated with a 5-week course of IV Ampicillin from negative cultures and suffered no complications. We also conducted a thorough literature review through PubMed and Google Scholar, which yielded a mere 15 reported cases of HI-IE. Fourteen of the reported HI-IE cases included epidemiological data, showing no gender predominance. The mean age of the subjects was 39.5, with the mitral valve being the most implicated (64%) and tricuspid valve involvement being rare (21%). Native tricuspid valve IE is an uncommon entity, especially in the absence of IV drug use. Haemophilus influenzae is an extremely rare cause of IE, with a literature review showing merely 15 reported cases. This article cites the 16th case of HI-IE published in the literature. © 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.

Citation

Nadim Jaafar, Akshay Duddu, Siddartha Guru, Ibukunolupo Oni. Haemophilus influenzae endocarditis: a case report and literature review. Infection. 2024 Aug;52(4):1621-1625