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Cold denaturation of DNA origami nanostructures.
Daniel Dornbusch, Marcel Hanke, Emilia Tomm, Charlotte Kielar, Guido Grundmeier, Adrian Keller, Karim Fahmy
Chemical communications (Cambridge, England) 2024 May 23Sizes of these terms reflect their relevance to your search.
The coupling of structural transitions to heat capacity changes leads to destabilization of macromolecules at both elevated and lowered temperatures. DNA origami not only exhibit this property but also provide a nanoscopic observable of cold denaturation processes by directing intramolecular strain to the most sensitive elements within their hierarchical architecture.
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Daniel Dornbusch, Marcel Hanke, Emilia Tomm, Charlotte Kielar, Guido Grundmeier, Adrian Keller, Karim Fahmy. Cold denaturation of DNA origami nanostructures. Chemical communications (Cambridge, England). 2024 May 23;60(43):5590-5593
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PMID: 38666465
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