Multi-layered effects of Panax notoginseng on immune system.

Chunhao Yang, Liping Qu, Rui Wang, Feifei Wang, Zhaoxiang Yang, Fengkun Xiao

Pharmacological research 2024 Jun

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Recent research has demonstrated the immunomodulatory potential of Panax notoginseng in the treatment of chronic inflammatory diseases and cerebral hemorrhage, suggesting its significance in clinical practice. Nevertheless, the complex immune activity of various components has hindered a comprehensive understanding of the immune-regulating properties of Panax notoginseng, impeding its broader utilization. This review evaluates the effect of Panax notoginseng to various types of white blood cells, elucidates the underlying mechanisms, and compares the immunomodulatory effects of different Panax notoginseng active fractions, aiming to provide the theory basis for future immunomodulatory investigation. Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.

Citation

Chunhao Yang, Liping Qu, Rui Wang, Feifei Wang, Zhaoxiang Yang, Fengkun Xiao. Multi-layered effects of Panax notoginseng on immune system. Pharmacological research. 2024 Jun;204:107203