Novel Insights on Group B Streptococcus in Pregnancy.

Ethan Litman, Brett Young, Melissa Spiel

Clinical obstetrics and gynecology 2024 Sep 01

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Group B Streptococcus (GBS) is a frequent colonizer of the human genital and gastrointestinal tract. In pregnant or postpartum persons, colonization is often asymptomatic and can contribute to infectious morbidity in both the parturient and the newborn. The prevalence of invasive GBS disease has dramatically decreased over the past 3 decades. However, despite standardized clinical algorithms, GBS disease remains a public health concern. Our review summarizes the GBS bacteria pathophysiology, morbidity, management guidelines, and summarizes ongoing research. While novel testing and parturient vaccination are being explored, barriers exist, preventing guideline updates and widespread implementation. Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

Citation

Ethan Litman, Brett Young, Melissa Spiel. Novel Insights on Group B Streptococcus in Pregnancy. Clinical obstetrics and gynecology. 2024 Sep 01;67(3):633-643