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Detecting Amyloid Goiter With 99mTc-PYP SPECT/CT in the Setting of Ankylosing Spondylitis: An Uncommon Involvement of AA Amyloidosis.

Dilara Denizmen, Artur Salmaslioglu, Dogu Vuralli Bakkaloglu, Duygu Has Simsek, Yasemin Sanli

Clinical nuclear medicine 2024 Aug 01


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  • aa amyloidosis (3)
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  • goiter (3)
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    We present a case with systemic amyloidosis secondary to ankylosing spondylitis (AA amyloidosis), whose 99mTc PYP scintigraphy revealed amyloid deposition in the thyroid gland (amyloid goiter). Amyloidosis is characterized by extracellular accumulation of amyloid fibril proteins leading to organ malfunction. Even though AA amyloidosis can be observed in patients with systemic inflammatory diseases, it is a very rare complication in ankylosing spondylitis. SPECT/CT images showed diffuse tracer uptake in enlarged thyroid gland containing fat density areas. Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

    Citation

    Dilara Denizmen, Artur Salmaslioglu, Dogu Vuralli Bakkaloglu, Duygu Has Simsek, Yasemin Sanli. Detecting Amyloid Goiter With 99mTc-PYP SPECT/CT in the Setting of Ankylosing Spondylitis: An Uncommon Involvement of AA Amyloidosis. Clinical nuclear medicine. 2024 Aug 01;49(8):e399-e400

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    PMID: 38967510

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    • Copyright © 2024 Illumina Inc. All rights reserved.