Evgeny Lian, Robert Pantlik, Vera Maslova, Sven Willert, Fabian Moser, Andrew Remppis, Derk Frank, Thomas Demming
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2024 Jul 12Local tissue impedance drop (LID) and lesion size index (LSI) technologies are valuable for predicting effective lesion formation. This study compares the acute and long-term efficacy of LID-guided versus LSI-guided pulmonary vein isolation (PVI) for atrial fibrillation treatment. We retrospectively analyzed two patient groups undergoing radiofrequency PVI. In the LID-guided group (n = 35), ablation was performed without contact force monitoring, stopping at the LID plateau (target LID 12 Ohm posterior, 16 Ohm anterior). In the LSI-guided group (n = 31), ablation used contact force information with target LSI (5 anterior, 4 posterior). Both groups utilized a power of 40 W anterior and 30 W posterior, with < 6 mm inter-lesion distance. Gap mapping and touch-up ablation were done if necessary. PVI was achieved with a significantly shorter ablation time in the LSI-guided group (25 min [21;31] vs 30 [27;35], p = 0.035). PV gaps were more frequent in the LID-guided group (74% vs 42%, p = 0.016). Over 11.5 ± 2.9 months follow-up, arrhythmia recurrence was higher in the LID-guided group (34.3% vs 16.1%, p = 0.037). A redo procedure performed in 10 (28.6%) patients in the LID-guided group and 3 (9.7%) in the LSI-guided group showed chronic PV reconnections in 7 out of 10 (70%) and 2 out of 3 (67%) patients, respectively. LSI-guided ablation results in shorter ablation time and fewer PV gaps compared to LID-guided ablation. Despite initial success, LID-guided ablation had higher arrhythmia recurrence and PV reconnections during long-term follow-up compared to LSI-guided ablation. © 2024. The Author(s).
Evgeny Lian, Robert Pantlik, Vera Maslova, Sven Willert, Fabian Moser, Andrew Remppis, Derk Frank, Thomas Demming. Local impedance drop-guided versus lesion size index-guided pulmonary vein isolation. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing. 2024 Jul 12
PMID: 38995604
View Full Text