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Immunoglobulin A (IgA) vasculitis, or Henoch-Schonlein purpura, is the most common systemic vasculitis in children, clinically presenting as palpable purpura in combination with arthritis, gastrointestinal involvement, or kidney injury. Subcutaneous edema is reported in patients with IgA vasculitis, and it commonly affects the lower extremities, especially around joints. Here, we report a case of IgA vasculitis with a rare presentation of edema isolated to the periorbital area in a 7-year-old boy, who subsequently developed crescentic glomerulonephritis with nephrotic range proteinuria. Isolated periorbital edema is an uncommon cutaneous feature of IgA vasculitis. © 2024 Wiley Periodicals LLC.

Citation

Le Wen Chiu, Basema I Dibas, Patrick D Walker, Aimee C Smidt, Nikifor K Konstantinov. Immunoglobulin A vasculitis with periorbital edema and severe renal involvement: A case report. Pediatric dermatology. 2025 Jan-Feb;42(1):129-132

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PMID: 39169477

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