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An intrinsically disordered region in MED13 turns Mediator on/off on cue.

Vincent Villeret, Didier Monté, Alexis Verger

Molecular cell 2024 Aug 22


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    Complementary studies by Zhao et al.1 and Chen et al.2 reveal how an intrinsically disordered region in MED13 controls mutually exclusive binding of RNA Polymerase II and CDK8 kinase module to Mediator, switching Mediator and transcription activation on and off. Copyright © 2024 Elsevier Inc. All rights reserved.

    Citation

    Vincent Villeret, Didier Monté, Alexis Verger. An intrinsically disordered region in MED13 turns Mediator on/off on cue. Molecular cell. 2024 Aug 22;84(16):3005-3007

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    PMID: 39178836

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    • Copyright © 2024 Illumina Inc. All rights reserved.