Versatility of OnabotulinumtoxinA in Aesthetic Medicine.

OnabotulinumtoxinA is an injectable product that was introduced into medicine in the 1970s and has been the subject of thousands of clinical and nonclinical publications. To review the data related to the versatility of onabotulinumtoxinA in medical aesthetics. PubMed was searched to identify literature evaluating the effects of onabotulinumtoxinA, with preference given to randomized, placebo-controlled trials and safety meta-analyses. OnabotulinumtoxinA is effective and safe across multiple facial indications, racial and ethnic groups, age groups, genders, and facial line severities. Patient-reported outcomes have been prioritized in aesthetic clinical trials and indicate high patient satisfaction and appearance-related psychological outcomes. Integrated safety meta-analysis and immunogenicity analyses have documented acceptable adverse event rates and low immunogenicity of onabotulinumtoxinA. OnabotulinumtoxinA is a versatile aesthetic product supported by a strong literature base and positive physician and patient-reported outcomes that reflect a meaningful impact on patient's quality of life. Copyright © 2024 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

Citation

Mitchell F Brin, John Maltman, Mary Ann Chapman, Sara Sangha. Versatility of OnabotulinumtoxinA in Aesthetic Medicine. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2024 Sep 01;50(9S):S12-S17

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PMID: 39196828

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