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    In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999-2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002-2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes to ACVs could increase PRN-deficient B. pertussis and infections.

    Citation

    Alex-Mikael Barkoff, Tamara Kastrin, Katja Seme, Marta Grgič Vitek, Jussi Mertsola, Qiushui He. Prevalence of Pertactin-Deficient Bordetella pertussis Isolates, Slovenia. Emerging infectious diseases. 2024 Nov;30(11):2429-2432

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    PMID: 39447192

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