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Flipping a switch on BRD4: How to control the do-it-all.
Femke A H van Hout, Anniina Vihervaara
Molecular cell 2024 Nov 21
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In this issue, Devaiah et al.1 identify JNK-catalyzed phosphorylation to convert bromodomain-containing protein 4 (BRD4) from a chromatin regulator to a transcription activator. Copyright © 2024 Elsevier Inc. All rights reserved.
Citation
Femke A H van Hout, Anniina Vihervaara.
Flipping a switch on BRD4: How to control the do-it-all.
Molecular cell.
2024 Nov 21;84(22):4257-4259
Mesh Tags
Transcription Factors
Humans
Phosphorylation
Cell Cycle Proteins
Nuclear Proteins
Chromatin
Bromodomain Containing Proteins
Substances
Transcription Factors
BRD4 protein, human
Cell Cycle Proteins
Nuclear Proteins
Chromatin
Bromodomain Containing Proteins
PMID: 39577398
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