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Advances in laboratory diagnosis of Sjogren's disease in children.

Yuemeng Li, Wenxiu He, Yu Zhou, Haotian Chen, Pengyue You, Danni Mu, Yichen Ma, Yumeng Gao, Kaiduo Xu, Haitao Dong, Xinqi Cheng

Clinica chimica acta; international journal of clinical chemistry 2025 Feb 01


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    Sjogren's disease (SjD) in children is a rare chronic autoimmune disease not fully recognized due to clinical manifestations different from adults. As such, new objective indicators are needed to supplement existing markers and assist in diagnosis. This review summarizes pathogenesis of SjD in children, current diagnostic criteria and research progress in laboratory diagnosis including serologic testing, saliva and tear analysis, histopathological examination as well as emerging markers of interest. Copyright © 2024 Elsevier B.V. All rights reserved.

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    Yuemeng Li, Wenxiu He, Yu Zhou, Haotian Chen, Pengyue You, Danni Mu, Yichen Ma, Yumeng Gao, Kaiduo Xu, Haitao Dong, Xinqi Cheng. Advances in laboratory diagnosis of Sjogren's disease in children. Clinica chimica acta; international journal of clinical chemistry. 2025 Feb 01;567:120095

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    PMID: 39681228

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