Increasing the biomolecular relevance of cell culture practice.

The biomolecular relevance of medium supplements is a key challenge affecting cell culture practice. The biomolecular composition of commonly used supplements differs from that of a physiological environment, affecting the validity of conclusions drawn from in vitro studies. This article discusses the advantages and disadvantages of common supplements, including context-dependent considerations for supplement selection to improve biomolecular relevance, especially in nanomedicine and extracellular vesicle research. © 2025. The Author(s).

Citation

Raluca E Ghebosu, Lawrence Hui, Joy Wolfram. Increasing the biomolecular relevance of cell culture practice. Journal of biomedical science. 2025 Jan 03;32(1):3

Mesh Tags

Substances

PMID: 39748368

search → result