EWSR1::BEND2 Adenocarcinoma with Hyaline Pseudorosettes of the Trachea.

We describe the novel occurrence of a adenocarcinoma involving the trachea, with distinct solid and glandular components, in a 34-year-old patient. We illustrate its morphological and immunophenotypic features and describe the molecular finding of an EWSR1::BEND2 gene fusion detected by next-generation sequencing (NGS). We discuss the findings in comparison to BEND2-fusion associated neoplasms reported in the head and neck region in the literature to date. © 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Citation

Juan J Sanchez-Ramirez, Matthew R Hoffman, John C Keech, Anthony N Snow, Andrew M Bellizzi, Anand Rajan. EWSR1::BEND2 Adenocarcinoma with Hyaline Pseudorosettes of the Trachea. Head and neck pathology. 2025 Jan 07;19(1):7

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PMID: 39775186

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