Chapter 3: Impact of primary hyperparathyroidism.

At present, primary hyperparathyroidism is most often discovered in an asymptomatic patient, but can sometimes be revealed by a renal or bone complications. In all cases, a full work-up is recommended, with assessment of renal function (glomerular filtration rate), 24-hour calciuria, screening for risk factors for lithiasis, and renal and urinary tract imaging (ultrasound or CT scan) to look for stones or nephrocalcinosis. Bone densitometry, with measurements of the spine, femur and radius, is the recommended reference test for demineralization. Standard X-rays of the spine or other imaging techniques are recommended for the detection of asymptomatic vertebral fracture. Neurocognitive manifestations, reduced quality of life or cardiovascular manifestations should not be routinely screened for, as they are not currently consensual criteria for surgical indications. Copyright © 2025. Published by Elsevier Masson SAS.

Citation

Nicolas Scheyer, Samuel Frey, Eugénie Koumakis, Carole Guérin, Rachel Desailloud, Lionel Groussin, Bertrand Cariou, Bruno Vergès, Laurent Brunaud, Eric Mirallié, Lucile Figueres, Hélène Lasolle. Chapter 3: Impact of primary hyperparathyroidism. Annales d'endocrinologie. 2025 Feb;86(1):101692

Mesh Tags

PMID: 39818288

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