An unusual association: gastric xanthelasma presenting with iron deficiency anemia: a case report.

Gastric xanthelasma is a rare, benign lesion with uncertain clinical significance. Despite its asymptomatic nature, it may coexist with conditions like chronic gastritis and iron deficiency anemia. A 71-year-old Turkish male presented with iron deficiency anemia, chronic fatigue, and upper abdominal pain. Endoscopy revealed yellowish-white plaques (2-6 mm) on the antral mucosa, confirmed as gastric xanthelasma on histopathology. Concurrently, a rectal sessile polyp was excised during colonoscopy. The patient recovered following a 3-month course of oral iron supplementation and proton pump inhibitors. Follow-up endoscopy showed resolution of gastric lesions. This report underscores the diagnostic importance of endoscopy and biopsy in patients with unexplained anemia and highlights the potential association between gastric xanthelasma and ron deficiency anemia, warranting further research. © 2025. The Author(s).

Citation

Yuksel Dogan, Adnan Mesut Dede, Arzu Erdoğan. An unusual association: gastric xanthelasma presenting with iron deficiency anemia: a case report. Journal of medical case reports. 2025 Mar 04;19(1):98

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PMID: 40038797

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