Acute interstitial nephritis is a rare complication of treatment with non-steroidal antiinflammatory drugs. A case is reported with severe, reversible, non-oliguric renal failure caused by biopsy-proven acute interstitial nephritis after therapy with mefenamic acid (Ponstan). Prednisone treatment resulted in normalization of renal function within 4 weeks.
K Brunner, H R Burger, P Greminger, R Streuli. Mefenamic acid (Ponstan)-induced acute interstitial nephritis with reversible, severe, non-oliguric renal failure]. Schweizerische medizinische Wochenschrift. 1985 Nov 30;115(48):1730-4
PMID: 4081705
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