Toxicity of an original antiemetic preparation dimetpramid].

A new original drug dimetpramid injected per os into mice and rats exhibits moderate toxicity, exerts a weak irritating action on the mucous membranes. The drug is capable of penetrating via the unaffected skin, producing systemic effects. With all routes of administration the drug may have a moderate inhibitory action on ovarian function and the manifestation of the hypotensive effect.

Citation

T M Orlova, G V Tsarichenko, V V Malochkin, V I Legeza, M G Shagoian. Toxicity of an original antiemetic preparation dimetpramid]. Farmakologiia i toksikologiia. 1985 Nov-Dec;48(6):74-6

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PMID: 4085635

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