Pharmacological studies of a new analgesic, dl-erythro-1-phenyl-2-(o-chlorophenyl)-2-[4-(p-methoxybenzyl)-1-piperazinyl] ethanol dihydrochloride, in experimental animals.

H Nakamura, K Ishii, Y Yokoyama, S Motoyoshi, C Imazu, M Shimizu

Experientia 1979 Mar 15

filter terms:

dl-Erythro-1-phenyl-2-(o-chlorophenyl)-2-[4-(p-methoxybenzyl)-1-piperazinyl] ethanol dihydrochloride showed orally a definite analgesic activity, without producing the significant morphine-like physical dependence liability, and its analgesic potency was about a half that of codeine and far superior to aminopyrine in experimental animals.

Citation

H Nakamura, K Ishii, Y Yokoyama, S Motoyoshi, C Imazu, M Shimizu. Pharmacological studies of a new analgesic, dl-erythro-1-phenyl-2-(o-chlorophenyl)-2-[4-(p-methoxybenzyl)-1-piperazinyl] ethanol dihydrochloride, in experimental animals. Experientia. 1979 Mar 15;35(3):369-70