Immunomodulating effects in vitro of a hydroxythiazolobenzimidazole in the absence of mitogenicity.

G H Warren, L Mills, H Friedman

Experientia 1978 Jun 15

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Wy-13, 876, a hydroxythiazolobenzimidazole, enhanced in vitro antibody formation by mouse spleen cells immunized with sheep red blood cells. The optimal dose was 25--50 microgram/culture. The compound did not have a mitogenic effect at any dose.

Citation

G H Warren, L Mills, H Friedman. Immunomodulating effects in vitro of a hydroxythiazolobenzimidazole in the absence of mitogenicity. Experientia. 1978 Jun 15;34(6):802-3