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A rare retroperitoneal malignant xanthogranuloma is described. The patient developed malignant bone lesions followed by brain localization, and died three years later. At autopsy a very large cystic retroperitoneal tumor with osteolytic lesion of sacrum was found. A review of cases diagnosed as retroperitoneal xanthogranuloma indicates that this lesion seems to be a particular form of the wide group of malignant fibrous histiocytoma with xanthomatous and inflammatory cells. Moreover it could be a primary malignant fibrous histiocytoma of bone. Furthermore, difficulties of differential diagnosis of these tumors are discussed mainly with histiocytosis X.

Citation

M Briffod, J Berlie, B Clavel, H Hébert. Retroperitoneal malignant xanthogranuloma (author's transl)]. La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris. 1982 Jan 14;58(2):113-9

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PMID: 6276995

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