Studies on new antiplatelet agents, WS-30581 A and B.

K Umehara, K Yoshida, M Okamoto, M Iwami, H Tanaka, M Kohsaka, H Imanaka

The Journal of antibiotics 1984 Oct

filter terms:

WS-30581 A and B are antiplatelet agents produced by a strain of Streptoverticillium waksmanii. The compounds were purified by solvent extraction and column chromatography, and identified as new pimprinine analogs on the basis of their physico-chemical properties. The producing organism produced pimprinine along with these compounds. Pimprinine and the two new analogs have potent inhibitory effects on platelet aggregation.

Citation

K Umehara, K Yoshida, M Okamoto, M Iwami, H Tanaka, M Kohsaka, H Imanaka. Studies on new antiplatelet agents, WS-30581 A and B. The Journal of antibiotics. 1984 Oct;37(10):1153-60