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Variations of blood 11-HOCS and tyrosine suggested as an indicator of tissue glucocorticoid provision were investigated in 54 patients with acute myocardial infarction (AMI). Where AMI takes a favourable course, the adrenocortical activity meets bodily requirements in about 25% of patients, whereas 30% show states of transitory hormonal deficit during the first 4-5 days of the disease. In severe AMI with multiple combined complications, tissue glucocorticoid deficiency was found in 73% of patients, the majority of those having high blood 11-HOCS levels. A profound disorder of the glucocorticoid control of metabolic processes is suggested.

Citation

I T Rass, R M Zaslavskaia, A B Kazarian, O M Shekhaeva, A F Kon'kova. Level of tyrosine in the blood of patients with acute myocardial infarction during the assessment of corticosteroid hormone production]. Kardiologiia. 1983 Jul;23(7):72-6

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PMID: 6620817

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