J Straczek, F Maachi, D Le Nguyen, M Becchi, M H Heulin, P Nabet, F Belleville
Biochemistry Laboratory, Faculty of Medicine, University of Nancy I, Vandoeuvre, France.
FEBS letters 1995 Oct 16Human plasma has been shown to contain a low molecular weight factor that potentiates human IGF-I stimulation of glycosaminoglycan synthesis in chick embryo cartilage. The peptide was purified and characterized by Edman degradation and electrospray mass spectrometry. The primary structure determined was: Trp-Gly-His-Glu. A homologous synthetic peptide similarly promoted matrix biosynthesis in cartilage exposed to IGF-I.
J Straczek, F Maachi, D Le Nguyen, M Becchi, M H Heulin, P Nabet, F Belleville. Purification from human plasma of a tetrapeptide that potentiates insulin-like growth factor-I activity in chick embryo cartilage. FEBS letters. 1995 Oct 16;373(3):207-11
PMID: 7589467
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